Champions Medeama SC have been handed a demanding schedule in their bid to retain the 2026/27 Ghana Premier League title, with an opening-day away clash against Dreams FC highlighting a tough start to the new campaign.

Fresh from lifting their second Premier League crown, the Mauve and Yellow will be eager to establish themselves as Ghana’s dominant force. However, their quest for successive league titles will require navigating one of the toughest fixture lists in the division.

Medeama begin their title defence on the road before returning to the TnA Stadium for their first home fixture against newly promoted Port City FC. They then travel to Tema to face Vision FC before hosting Basake Holy Stars in the first Western Derby of the season on Matchday Four.

The early tests continue with another away assignment against fellow newcomers Debibi United FC, ensuring the champions have little room for error during the opening weeks of the campaign.

Regional supremacy will once again be at stake as Medeama prepare for a series of high-profile Western derbies. The Tarkwa-based outfit travel to FC Samartex 1996 on Matchday Seven in one of the standout fixtures of the first round before welcoming Bibiani Gold Stars to the TnA Stadium on Matchday 15 in another clash expected to have major implications at both ends of the table.

A major highlight of Medeama’s schedule comes on Matchday Nine, when they travel to Kumasi for a heavyweight showdown against Asante Kotoko. The much-anticipated encounter, scheduled for the October 30November 2, 2026 weekend, could provide an early indication of the balance of power in the title race.

The champions’ title defence will conclude with a blockbuster final-day encounter away to Hearts of Oak in Accra. Depending on the standings, the clash could prove decisive in determining the destination of the Premier League trophy.



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